Abbott Nutrition study: Older women gain greater muscle benefits from protein plus HMB

A randomized crossover trial in Nutrients found that adding TSI’s beta-hydroxy-beta-methylbutyrate (HMB) to a 40 g whey protein drink increased muscle protein synthesis (MPS) in older women and prolonged the suppression of muscle protein breakdown (MPB) in both sexes. The results suggest HMB may help overcome anabolic resistance and enhance muscle health in older adults, particularly improving muscle-building responses in women compared with protein alone.