Body weight may influence coffee’s effects on heart and metabolic health

Coffee's effects on heart health and metabolic health may vary according to body weight, with new research suggesting that BMI influences how caffeinated and decaffeinated coffee affect the Sirt-1 and sRAGE pathways in adults with coronary artery disease. The findings indicate that lower BMI may be associated with greater Sirt-1 activation following caffeinated coffee consumption, highlighting a potential role for BMI in modulating coffee's effects on glucose metabolism, lipid metabolism, and cardiovascular health.