Research builds evidence for gut-muscle axis and proposes AI sarcopenia prediction tool

Researchers examined how probiotics may help prevent sarcopenia in older adults through the gut–muscle axis, focusing on muscle strength, muscle mass, inflammation, mitochondrial function and muscle growth. They combined NHANES, UK Biobank and GMrepo data with laboratory muscle-cell experiments, molecular docking and machine-learning AI models to investigate how probiotic-related bacteria and metabolites such as butyrate may support muscle health and predict sarcopenia risk.