Verb’s oat-based postbiotic may boost keystone microbiota and improve mood

A randomized, double-blind, placebo-controlled trial found that daily supplementation with Verb Biotics’ oat-based postbiotic, Keystone, enriched beneficial gut microbiota, reduced pro-inflammatory biomarkers, and improved emotional wellness in healthy adults over four weeks. Mechanistic studies showed the postbiotic works by enhancing gut barrier function, modulating immunity, and supporting keystone gut bacteria, without introducing new organisms. The trial reported significant enrichment of 33 beneficial species and reductions in 38 taxa linked to GI distress, alongside lower IL-8 and cortisol levels. These findings highlight the product’s potential as a targeted and precise approach to strengthening gut resilience and supporting the gut-brain axis.