Kidney Organoids Reveal Inflammatory Drivers of Diabetic Kidney Disease

In kidney organoids, elevated glucose triggered tissue-intrinsic inflammation and epithelial cell detachment without overt cytotoxicity. Inhibiting MIF, TNF-alpha, or MAPK-related signaling helped protect the organoids, suggesting inflammatory pathways may be targetable in diabetic kidney disease.

The post Kidney Organoids Reveal Inflammatory Drivers of Diabetic Kidney Disease appeared first on GEN - Genetic Engineering and Biotechnology News.