T-Cell Synapse Formation Is Restrained by PTPN22–PSTPIP1 Signaling

Wednesday, June 10, 2026Savannah WiegelView original

T‑cell synapse remodeling depends on actin dynamics via the PTPN22–PSTPIP1 axis. Understanding this axis could inform both autoimmune research and efforts to modulate T‑cell activation in cancer immunotherapy.

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